Human FCER2 ELISA Kit

Alternative name
Human BLAST-2 ELISA Kit;Human C-type lectin domain family 4 member J ELISA Kit;Human fc-epsilon-RII ELISA Kit;Human immunoglobulin E-binding factor ELISA Kit;Human lymphocyte IgE receptor ELISA Kit;Human CD23A ELISA Kit;Human CLEC4J ELISA Kit;Human FCE2 ELISA Kit;Human IGEBF ELISA Kit;Human CD23 ELISA Kit;Human Fc fragment of IgE receptor II ELISA Kit;Human low affinity immunoglobulin epsilon Fc receptor ELISA Kit;Human C-type lectin domain family 4, member J ELISA Kit;Human CD23 antigen ELISA Kit;Human Fc epsilon receptor II ELISA Kit;Human Fc fragment of IgE, low affinity II, receptor for (CD23) ELISA Kit;Human immunoglobulin epsilon-chain ELISA Kit;
Catalog
E007370
species
Human
GeneFCER2
Other Species Mouse Fcer2 ELISA Kit
SpecificityNatural and recombinant human CD23
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity< 10pg/ml
Intended UseHuman FCER2 ELISA Kit allows for the in vitro quantitative determination of FCER2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the assay: human CD23 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for CD23 has been precoated onto 96-well plates. Standards(NSO, D48-S321) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for CD23 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human CD23 amount of sample captured in plate. Background: CD23, also known as Fc epsilon RII, or FcepsilonRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23(FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.
Human Low affinity immunoglobulin epsilon Fc receptor soluble form Protein information
Uniprot ID FCER2_HUMAN
Uniprot AC P06734;
UniGene Hs.465778;
GeneID 2208
KEGG hsa:2208;
Human Low affinity immunoglobulin epsilon Fc receptor soluble form Protein SEQUENCE
SEQUENCE 321 AA; 36469 MW; F86708C0E6515B87 CRC64;
MEEGQYSEIE ELPRRRCCRR GTQIVLLGLV TAALWAGLLT LLLLWHWDTT
QSLKQLEERA ARNVSQVSKN LESHHGDQMA QKSQSTQISQ ELEELRAEQQ
RLKSQDLELS WNLNGLQADL SSFKSQELNE RNEASDLLER LREEVTKLRM
ELQVSSGFVC NTCPEKWINF QRKCYYFGKG TKQWVHARYA CDDMEGQLVS
IHSPEEQDFL TKHASHTGSW IGLRNLDLKG EFIWVDGSHV DYSNWAPGEP
TSRSQGEDCV MMRGSGRWND AFCDRKLGAW VCDRLATCTP PASEGSAESM
GPDSRPDPDG RLPTPSAPLH S
UCSC uc002mhm.3; human.;

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Human FCER2 ELISA Kit