Human CR2 ELISA Kit

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  • Alternative name

    Human Cr2 ELISA Kit;Human Complement C3d receptor ELISA Kit;Human Epstein-Barr virus receptor ELISA Kit;Human EBV receptor ELISA Kit;Human C3DR ELISA Kit;Human CD21 ELISA Kit;Human CR ELISA Kit;Human CVID7 ELISA Kit;Human SLEB9 ELISA Kit;Human complement C3d receptor 2 ELISA Kit;Human complement receptor type 2 ELISA Kit;Human complement component (3d/Epstein Barr virus) receptor 2 ELISA Kit;Human complement component 3d receptor 2 ELISA Kit;

  • Catalog
    E007361
  • species
    Human
  • GeneCR2
  • Other Species Mouse Cr2 ELISA Kit
  • SpecificityThe Human CD21 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CD21 proteins within the range of 780 pg/ml - 50000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity20 pg/ml.
  • Intended UseHuman CR2 ELISA Kit allows for the in vitro quantitative determination of CR2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay||The Human CD21 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human CD21 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human CD21 coated on a 96-well plate. Standards and samples are pipetted into the wells and CD21 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human CD21 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CD21 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Complement receptor type 2(CR2), also known as C3DR or CD21, is a protein that in humans is encoded by the CR2 gene. It is mapped to 1q32.2. CR2 is involved in the complement system. It binds to iC3b(inactive derivative of C3b), C3dg, or C3d. CR2 is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. CR2, together with CD19, CD81, and CD225, forms the B-cell coreceptor complex, which lowers the activation threshold of the B-cell antigen receptor. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9).
  • Human Complement receptor type 2 Protein information
  • Uniprot ID CR2_HUMAN
  • Uniprot AC P20023; C9JHD2; Q13866; Q14212; Q53EL2; Q5BKT9; Q5SR46; Q5SR48;
  • UniGene Hs.445757;
  • GeneID 1380
  • KEGG hsa:1380;
  • Human Complement receptor type 2 Protein SEQUENCE
  • SEQUENCE 1033 AA; 112916 MW; 7D89DB4A07847E9A CRC64;

    MGAAGLLGVF LALVAPGVLG ISCGSPPPIL NGRISYYSTP IAVGTVIRYS

    CSGTFRLIGE KSLLCITKDK VDGTWDKPAP KCEYFNKYSS CPEPIVPGGY

    KIRGSTPYRH GDSVTFACKT NFSMNGNKSV WCQANNMWGP TRLPTCVSVF

    PLECPALPMI HNGHHTSENV GSIAPGLSVT YSCESGYLLV GEKIINCLSS

    GKWSAVPPTC EEARCKSLGR FPNGKVKEPP ILRVGVTANF FCDEGYRLQG

    PPSSRCVIAG QGVAWTKMPV CEEIFCPSPP PILNGRHIGN SLANVSYGSI

    VTYTCDPDPE EGVNFILIGE STLRCTVDSQ KTGTWSGPAP RCELSTSAVQ

    CPHPQILRGR MVSGQKDRYT YNDTVIFACM FGFTLKGSKQ IRCNAQGTWE

    PSAPVCEKEC QAPPNILNGQ KEDRHMVRFD PGTSIKYSCN PGYVLVGEES

    IQCTSEGVWT PPVPQCKVAA CEATGRQLLT KPQHQFVRPD VNSSCGEGYK

    LSGSVYQECQ GTIPWFMEIR LCKEITCPPP PVIYNGAHTG SSLEDFPYGT

    TVTYTCNPGP ERGVEFSLIG ESTIRCTSND QERGTWSGPA PLCKLSLLAV

    QCSHVHIANG YKISGKEAPY FYNDTVTFKC YSGFTLKGSS QIRCKADNTW

    DPEIPVCEKE TCQHVRQSLQ ELPAGSRVEL VNTSCQDGYQ LTGHAYQMCQ

    DAENGIWFKK IPLCKVIHCH PPPVIVNGKH TGMMAENFLY GNEVSYECDQ

    GFYLLGEKKL QCRSDSKGHG SWSGPSPQCL RSPPVTRCPN PEVKHGYKLN

    KTHSAYSHND IVYVDCNPGF IMNGSRVIRC HTDNTWVPGV PTCIKKAFIG

    CPPPPKTPNG NHTGGNIARF SPGMSILYSC DQGYLLVGEA LLLCTHEGTW

    SQPAPHCKEV NCSSPADMDG IQKGLEPRKM YQYGAVVTLE CEDGYMLEGS

    PQSQCQSDHQ WNPPLAVCRS RSLAPVLCGI AAGLILLTFL IVITLYVISK

    HRARNYYTDT SQKEAFHLEA REVYSVDPYN PAS

  • UCSC uc001hfv.4; human. [P20023-1];


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