Human SDC1 ELISA Kit

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  • Alternative name

    Human SYND1 ELISA Kit;Human SDC ELISA Kit;Human CD138 ELISA Kit;Human syndecan ELISA Kit;Human syndecan 1 ELISA Kit;Human syndecan-1 ELISA Kit;Human CD138 antigen ELISA Kit;Human heparan sulfate proteoglycan fibroblast growth factor receptor ELISA Kit;Human syndecan proteoglycan 1 ELISA Kit;

  • Catalog
    E007293
  • species
    Human
  • GeneSDC1
  • Other Species Human SDC1/CD138 ELISA KitMouse Sdc1 ELISA KitMouse SDC1/CD138 ELISA KitBovine SDC1 ELISA KitHamster SDC1 ELISA KitRat Sdc1 ELISA Kit
  • SpecificityThe Human CD138 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CD138 proteins within the range of 156 pg/ml - 10000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseHuman SDC1 ELISA Kit allows for the in vitro quantitative determination of SDC1 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay||The Human CD138 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human CD138 in Cell Culture Supernatants, Serum. This assay employs an antibody specific for Human CD138 coated on a 96-well plate. Standards and samples are pipetted into the wells and CD138 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human CD138 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CD138 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Syndecan 1, also known as SYND1 or CD138, is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane(type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. This gene is mapped to 2p24.1. The syndecans mediate cell binding, cell signaling, cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan 1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. What's more, Syndecan-1 is also a sponge for growth factors, with binding largely via heparan sulfate chains.
  • Human Syndecan-1 Protein information
  • Uniprot ID SDC1_HUMAN
  • Uniprot AC P18827; D6W523; Q53QV0; Q546D3; Q96HB7;
  • UniGene Hs.224607; Hs.665958;
  • GeneID 6382
  • KEGG hsa:6382;
  • Human Syndecan-1 Protein SEQUENCE
  • SEQUENCE 310 AA; 32462 MW; 8E9EF4A57F5FDBD0 CRC64;

    MRRAALWLWL CALALSLQPA LPQIVATNLP PEDQDGSGDD SDNFSGSGAG

    ALQDITLSQQ TPSTWKDTQL LTAIPTSPEP TGLEATAAST STLPAGEGPK

    EGEAVVLPEV EPGLTAREQE ATPRPRETTQ LPTTHLASTT TATTAQEPAT

    SHPHRDMQPG HHETSTPAGP SQADLHTPHT EDGGPSATER AAEDGASSQL

    PAAEGSGEQD FTFETSGENT AVVAVEPDRR NQSPVDQGAT GASQGLLDRK

    EVLGGVIAGG LVGLIFAVCL VGFMLYRMKK KDEGSYSLEE PKQANGGAYQ

    KPTKQEEFYA

  • UCSC uc002rdo.2; human.;




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