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Human CCL7 ELISA Kit

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  • Alternative name

    Human monocyte chemoattractant protein 3 ELISA Kit;Human monocyte chemotactic protein 3 ELISA Kit;Human MCP-3 ELISA Kit;Human NC28 ELISA Kit;Human small-inducible cytokine A7 ELISA Kit;Human MCP3 ELISA Kit;Human SCYA6 ELISA Kit;Human SCYA7 ELISA Kit;Human FIC ELISA Kit;Human MARC ELISA Kit;Human C-C motif chemokine ligand 7 ELISA Kit;Human C-C motif chemokine 7 ELISA Kit;Human chemokine (C-C motif) ligand 7 ELISA Kit;Human small inducible cytokine A7 (monocyte chemotactic protein 3) ELISA Kit;
  • Catalog
    E007222
  • species
    Human
  • GeneCCL7
  • SpecificityNatural and recombinant human CCL7
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 1pg/ml
  • Intended UseHuman CCL7 ELISA Kit allows for the in vitro quantitative determination of CCL7 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the assay: human CCL7 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for CCL7 has been precoated onto 96-well plates. Standards (E.coli, Q24-L99) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for CCL7 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human CCL7 amount of sample captured in plate. Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, mapped the MCP3 gene to chromosome 17q11.2-q12.1 MCP3 was identified as a physiologicsubstrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, suggested that matrix metalloproteinases are both effectors and regulators of the inflammatory response.2
  • Human C-C motif chemokine 7 Protein information
  • Uniprot ID CCL7_HUMAN
  • Uniprot AC P80098; Q569J6;
  • UniGene Hs.251526;
  • GeneID 6354
  • KEGG hsa:6354;
  • Human C-C motif chemokine 7 Protein SEQUENCE

  • SEQUENCE 99 AA; 11200 MW; 96048B371C25D00E CRC64;

    MKASAALLCL LLTAAAFSPQ GLAQPVGINT STTCCYRFIN KKIPKQRLES

    YRRTTSSHCP REAVIFKTKL DKEICADPTQ KWVQDFMKHL DKKTQTPKL

  • UCSC uc002hhz.5; human.;



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