Mouse Tnfrsf11b ELISA Kit

Contact Us
  • Alternative name

    Mouse osteoclastogenesis inhibitory factor ELISA Kit;Mouse osteoprotegerin ELISA Kit;Mouse OCIF ELISA Kit;Mouse Opg ELISA Kit;Mouse TR1 ELISA Kit;Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) ELISA Kit;Mouse tumor necrosis factor receptor superfamily member 11B ELISA Kit;

  • Catalog
    E062563
  • species
    Mouse
  • GeneTnfrsf11b
  • Standard CurveMouse Tnfrsf11b ELISA Kit
  • Other Species Human TNFRSF11B ELISA KitBovine TNFRSF11B ELISA KitRat Tnfrsf11b ELISA Kit
  • SpecificityNatural and recombinant mouse OPG
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 5pg/ml
  • Intended UseMouse Tnfrsf11b ELISA Kit allows for the in vitro quantitative determination of Tnfrsf11b , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: mouse OPG ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for OPG has been precoated onto 96-well plates. Standards(NSO,E22-L401) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for OPG is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse OPG amount of sample captured in plate. Background: Osteoprotegerin (OPG) is identical to osteoclastogenesis inhibitory factor (OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis.1 OPG is considered to play an important rolein the regulation of bone resorption by modifying osteoclast differentiation.2 Osteoprotegerin is an independent riskfactor for the progression of atherosclerosis and onset of cardiovascular disease.3 It can act as a soluble factor inthe regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.4 OPG system may play a critical role in the development of osteolytic bone disease in multiplemyeloma and that targeting this system may have therapeutic potential.5 OPG also plays a role in the vascularsystem.6
  • Mouse Tumor necrosis factor receptor superfamily member 11B Protein information
  • Uniprot ID TR11B_MOUSE
  • Uniprot AC O08712; O70202;
  • UniGene Mm.15383;
  • GeneID 18383
  • KEGG mmu:18383;
  • Mouse Tumor necrosis factor receptor superfamily member 11B Protein SEQUENCE
  • SEQUENCE 401 AA; 45923 MW; CAA6102D3B312470 CRC64;

    MNKWLCCALL VLLDIIEWTT QETLPPKYLH YDPETGHQLL CDKCAPGTYL

    KQHCTVRRKT LCVPCPDHSY TDSWHTSDEC VYCSPVCKEL QSVKQECNRT

    HNRVCECEEG RYLEIEFCLK HRSCPPGSGV VQAGTPERNT VCKKCPDGFF

    SGETSSKAPC IKHTNCSTFG LLLIQKGNAT HDNVCSGNRE ATQKCGIDVT

    LCEEAFFRFA VPTKIIPNWL SVLVDSLPGT KVNAESVERI KRRHSSQEQT

    FQLLKLWKHQ NRDQEMVKKI IQDIDLCESS VQRHLGHSNL TTEQLLALME

    SLPGKKISPE EIERTRKTCK SSEQLLKLLS LWRIKNGDQD TLKGLMYALK

    HLKTSHFPKT VTHSLRKTMR FLHSFTMYRL YQKLFLEMIG NQVQSVKISC

    L

  • UCSC uc007vrk.1; mouse.;



Inquiry About Mouse Tnfrsf11b ELISA Kit If you hope to order it or contact us directly, please contact us via sales@biobool.com. We will get back to you in 12hrs,Thanks!