Mouse Il23a ELISA Kit

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  • Alternative name

    Mouse IL-23 subunit alpha ELISA Kit;Mouse IL-23-A ELISA Kit;Mouse interleukin-23 subunit p19 ELISA Kit;Mouse IL-23p19 ELISA Kit;Mouse IL-23 ELISA Kit;Mouse p19 ELISA Kit;Mouse interleukin 23, alpha subunit p19 ELISA Kit;Mouse interleukin-23 subunit alpha ELISA Kit;

  • Catalog
    E056346
  • species
    Mouse
  • GeneIl23a
  • Standard CurveMouse Il23a ELISA Kit
  • Other Species Human IL23A ELISA KitGuinea Pig IL23A ELISA KitHorse IL23A ELISA KitPorcine IL23A ELISA KitRat Il23a ELISA Kit
  • SpecificityNatural and recombinant mouse IL-23
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 2pg/ml
  • Intended UseMouse Il23a ELISA Kit allows for the in vitro quantitative determination of Il23a , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: mouse IL-23 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for IL-23 has been precoated onto 96-well plates. Standards(sf21, (M23-S335)+(L20-A196)) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for IL-23 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse IL-23 amount of sample captured in plate. Background: Interleukin-23 subunit alpha(IL-23) is a protein that in humans is encoded by the IL23A gene. IL-23 is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration. Recently, IL-23 has been implicated in the development of cancerous tumors. The International Radiation Hybrid Mapping Consortium mapped the p19 gene to chromosome 12 (stSG47812).
  • Mouse Interleukin-23 subunit alpha Protein information
  • Uniprot ID IL23A_MOUSE
  • Uniprot AC Q9EQ14;
  • UniGene Mm.125482;
  • GeneID 83430
  • KEGG mmu:83430;
  • Mouse Interleukin-23 subunit alpha Protein SEQUENCE
  • SEQUENCE 196 AA; 22071 MW; DAF4A318A2DD3B7C CRC64;

    MLDCRAVIML WLLPWVTQGL AVPRSSSPDW AQCQQLSRNL CMLAWNAHAP

    AGHMNLLREE EDEETKNNVP RIQCEDGCDP QGLKDNSQFC LQRIRQGLAF

    YKHLLDSDIF KGEPALLPDS PMEQLHTSLL GLSQLLQPED HPRETQQMPS

    LSSSQQWQRP LLRSKILRSL QAFLAIAARV FAHGAATLTE PLVPTA

  • UCSC uc007hmc.1; mouse.;


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