Mouse Rarres2 ELISA Kit

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  • Alternative name

    Mouse chemerin ELISA Kit;Mouse 0610007L05Rik ELISA Kit;Mouse AI303516 ELISA Kit;Mouse retinoic acid receptor responder (tazarotene induced) 2 ELISA Kit;Mouse retinoic acid receptor responder protein 2 ELISA Kit;

  • Catalog
    E048087
  • species
    Mouse
  • GeneRarres2
  • Other Species Human RARRES2 ELISA KitBovine RARRES2 ELISA KitHamster RARRES2 ELISA Kit
  • SpecificityNatural and recombinant mouse Chemerin
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 20pg/ml
  • Intended UseMouse Rarres2 ELISA Kit allows for the in vitro quantitative determination of Rarres2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: mouse Chemerin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for Chemerin has been precoated onto 96-well plates. Standards(E.coli, T20-K162) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Chemerin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse Chemerin amount of sample captured in plate. Background: Chemerin, also known as RARRES2 or TIG2, is a protein that in humans is encoded by the RARRES2 gene. It is mapped to 7q36.1. Chemerin is a potent chemoattractant specific for antigen-presenting cells that requires proteolytic activation and acts as a ligand for the G protein-coupled receptor CMKLR1(also known as ChemR23). It is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. What's more, the active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.
  • Mouse Retinoic acid receptor responder protein 2 Protein information
  • Uniprot ID RARR2_MOUSE
  • Uniprot AC Q9DD06; Q8CHU8;
  • UniGene Mm.28231;
  • GeneID 71660
  • KEGG mmu:71660;
  • Mouse Retinoic acid receptor responder protein 2 Protein SEQUENCE
  • SEQUENCE 162 AA; 18350 MW; 56FDE44B1BF167F3 CRC64;

    MKCLLISLAL WLGTVGTRGT EPELSETQRR SLQVALEEFH KHPPVQLAFQ

    EIGVDRAEEV LFSAGTFVRL EFKLQQTNCP KKDWKKPECT IKPNGRRRKC

    LACIKMDPKG KILGRIVHCP ILKQGPQDPQ ELQCIKIAQA GEDPHGYFLP

    GQFAFSRALR TK

  • UCSC uc009but.1; mouse.;


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