Mouse Ctla4 ELISA Kit

Alternative name
Mouse cytotoxic T-lymphocyte-associated antigen 4 ELISA Kit;Mouse Ctla-4 ELISA Kit;Mouse Cd152 ELISA Kit;Mouse Ly-56 ELISA Kit;Mouse cytotoxic T-lymphocyte-associated protein 4 ELISA Kit;Mouse cytotoxic T-lymphocyte protein 4 ELISA Kit;Mouse CD152 antigen ELISA Kit;
Catalog
E047605
species
Mouse
GeneCtla4
Other Species Human CTLA4 ELISA Kit Canine CTLA4 ELISA Kit Porcine CTLA4 ELISA Kit Rabbit CTLA4 ELISA Kit
SpecificityThe Mouse CD152 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse CD152 proteins within the range of 156 pg/ml - 10000 pg/ml.
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity10 pg/ml.
Intended UseMouse Ctla4 ELISA Kit allows for the in vitro quantitative determination of Ctla4 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the Assay||The Bioscience Mouse CD152 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse CD152 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse CD152 coated on a 96-well plate. Standards and samples are pipetted into the wells and CD152 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse CD152 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CD152 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152 (Cluster of differentiation 152), is a protein receptor that down regulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.
Mouse Cytotoxic T-lymphocyte protein 4 Protein information
Uniprot ID CTLA4_MOUSE
Uniprot AC P09793; Q9QZZ7;
UniGene Mm.390;
GeneID 12477
KEGG mmu:12477;
Mouse Cytotoxic T-lymphocyte protein 4 Protein SEQUENCE
SEQUENCE 223 AA; 24993 MW; 5318FAAF416F4685 CRC64;
MACLGLRRYK AQLQLPSRTW PFVALLTLLF IPVFSEAIQV TQPSVVLASS
HGVASFPCEY SPSHNTDEVR VTVLRQTNDQ MTEVCATTFT EKNTVGFLDY
PFCSGTFNES RVNLTIQGLR AVDTGLYLCK VELMYPPPYF VGMGNGTQIY
VIDPEPCPDS DFLLWILVAV SLGLFFYSFL VSAVSLSKML KKRSPLTTGV
YVKMPPTEPE CEKQFQPYFI PIN

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Mouse Ctla4 ELISA Kit

Mouse cytotoxic T-lymphocyte-associated antigen 4 ELISA Kit;Mouse Ctla-4 ELISA Kit;Mouse Cd152 ELISA Kit;Mouse Ly-56 ELISA Kit;Mouse cytotoxic T-lymphocyte-associated protein 4 ELISA Kit;Mouse cytotoxic T-lymphocyte protein 4 ELISA Kit;Mouse CD152 antigen ELISA Kit;