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Mouse Bdnf ELISA Kit

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  • Alternative name

    Mouse BDNF ELISA Kit;Mouse brain derived neurotrophic factor ELISA Kit;Mouse brain-derived neurotrophic factor ELISA Kit;
  • Catalog
    E045556
  • species
    Mouse
  • GeneBdnf
  • SpecificityThe Mouse BDNF ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse BDNF proteins within the range of 31.2 pg/ml - 2000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • SensitivityThe minimum detectable dose of Mouse BDNF is typically less than 2 pg/ml.
  • Intended UseMouse Bdnf ELISA Kit allows for the in vitro quantitative determination of Bdnf , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the assay: Brain-derived neurotrophic factor (BDNF) is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is a secreted protein with the molecular weight of 27.8kDa, consisting of 247 amino acids. It is known to promote neuronal survival and differentiation. BDNF shares substantial amino acid sequence identity with nerve growth factor (NGF). BDNF and neurotrophin-3 (NT-3) are two recently cloned neurotrophic factors that are homologous to NGF. mRNA products of the BDNF and NT-3 genes are detected in the adult human brain, suggesting that these proteins are involved in the maintenance of the adult nervous system. BDNF and other neurotrophins are critically involved in long-term potentiation (LTP). BDNF-mediated LTP is induced postsynaptically. BDNF has trophic effects on serotonergic (5-HT) neurons in the central nervous system. BDNF has an essential maintenance function in the regulation of anxiety-related behavior and in food intake through central mediators in both the basal and fasted state. It plays a role in treating breathing disorders such as respiratory insufficiency after spinal injury. The mature form of BDNF is identical in all mammals examined, and the gene encoding human BDNF to chromosome 11, band p13. Background: Sandwich Enzyme-Linked Immunosorbent Assay for Quantitative Detection of Mouse BDNF Concentrations in Cell Culture Supernatants, Serum, Plasma.
  • Mouse Brain-derived neurotrophic factor Protein information
  • Uniprot ID BDNF_MOUSE
  • Uniprot AC P21237;
  • UniGene Mm.1442;
  • GeneID 12064
  • KEGG mmu:12064;
  • Mouse Brain-derived neurotrophic factor Protein SEQUENCE

  • SEQUENCE 249 AA; 28123 MW; 90CE1F16BB235C97 CRC64;

    MTILFLTMVI SYFGCMKAAP MKEVNVHGQG NLAYPGVRTH GTLESVNGPR

    AGSRGLTTTS LADTFEHVIE ELLDEDQKVR PNEENHKDAD LYTSRVMLSS

    QVPLEPPLLF LLEEYKNYLD AANMSMRVRR HSDPARRGEL SVCDSISEWV

    TAADKKTAVD MSGGTVTVLE KVPVSKGQLK QYFYETKCNP MGYTKEGCRG

    IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV CTLTIKRGR

  • UCSC uc008lme.1; mouse.;



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