Mouse Axl ELISA Kit

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  • Alternative name

    Mouse adhesion-related kinase ELISA Kit;Mouse Ark ELISA Kit;Mouse Ufo ELISA Kit;Mouse AI323647 ELISA Kit;Mouse Tyro7 ELISA Kit;Mouse AXL receptor tyrosine kinase ELISA Kit;Mouse tyrosine-protein kinase receptor UFO ELISA Kit;Mouse ufo oncogene homolog ELISA Kit;

  • Catalog
    E045324
  • species
    Mouse
  • GeneAxl
  • Other Species Human AXL ELISA KitMouse AXL/UFO ELISA Kit
  • SpecificityThe Mouse AXL ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse AXL proteins within the range of 31.2 pg/ml - 2000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseMouse Axl ELISA Kit allows for the in vitro quantitative determination of Axl , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay||The Bioscience Mouse AXL ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse AXL in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse AXL coated on a 96-well plate. Standards and samples are pipetted into the wells and AXL present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse AXL antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of AXL bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene, which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants.
  • Mouse Tyrosine-protein kinase receptor UFO Protein information
  • Uniprot ID UFO_MOUSE
  • Uniprot AC Q00993; Q80YQ3;
  • UniGene Mm.4128;
  • GeneID 26362
  • KEGG mmu:26362;
  • Mouse Tyrosine-protein kinase receptor UFO Protein SEQUENCE
  • SEQUENCE 888 AA; 98191 MW; C5350E3A8995E975 CRC64;

    MGRVPLAWWL ALCCWGCAAH KDTQTEAGSP FVGNPGNITG ARGLTGTLRC

    ELQVQGEPPE VVWLRDGQIL ELADNTQTQV PLGEDWQDEW KVVSQLRISA

    LQLSDAGEYQ CMVHLEGRTF VSQPGFVGLE GLPYFLEEPE DKAVPANTPF

    NLSCQAQGPP EPVTLLWLQD AVPLAPVTGH SSQHSLQTPG LNKTSSFSCE

    AHNAKGVTTS RTATITVLPQ RPHHLHVVSR QPTELEVAWT PGLSGIYPLT

    HCNLQAVLSD DGVGIWLGKS DPPEDPLTLQ VSVPPHQLRL EKLLPHTPYH

    IRISCSSSQG PSPWTHWLPV ETTEGVPLGP PENVSAMRNG SQVLVRWQEP

    RVPLQGTLLG YRLAYRGQDT PEVLMDIGLT REVTLELRGD RPVANLTVSV

    TAYTSAGDGP WSLPVPLEPW RPGQGQPLHH LVSEPPPRAF SWPWWYVLLG

    ALVAAACVLI LALFLVHRRK KETRYGEVFE PTVERGELVV RYRVRKSYSR

    RTTEATLNSL GISEELKEKL RDVMVDRHKV ALGKTLGEGE FGAVMEGQLN

    QDDSILKVAV KTMKIAICTR SELEDFLSEA VCMKEFDHPN VMRLIGVCFQ

    GSDREGFPEP VVILPFMKHG DLHSFLLYSR LGDQPVFLPT QMLVKFMADI

    ASGMEYLSTK RFIHRDLAAR NCMLNENMSV CVADFGLSKK IYNGDYYRQG

    RIAKMPVKWI AIESLADRVY TSKSDVWSFG VTMWEIATRG QTPYPGVENS

    EIYDYLRQGN RLKQPVDCLD GLYALMSRCW ELNPRDRPSF AELREDLENT

    LKALPPAQEP DEILYVNMDE GGSHLEPRGA AGGADPPTQP DPKDSCSCLT

    AADVHSAGRY VLCPSTAPGP TLSADRGCPA PPGQEDGA

  • UCSC uc009ftx.2; mouse.;


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