Human MYD88 ELISA Kit

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  • Alternative name

    Human MYD88D ELISA Kit;Human myeloid differentiation primary response 88 ELISA Kit;Human myeloid differentiation primary response protein MyD88 ELISA Kit;Human mutant myeloid differentiation primary response 88 ELISA Kit;Human myeloid differentiation primary response gene (88) ELISA Kit;

  • Catalog
    E025251
  • species
    Human
  • GeneMYD88
  • SpecificityNatural and recombinant human MyD88
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman MYD88 ELISA Kit allows for the in vitro quantitative determination of MYD88 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: human MyD88 ELISA Kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for MyD88 has been precoated onto 96-well plates. Standards(E.coli, M1-P296) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for MyD88 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB are used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human MyD88 amount of sample captured in plate. Background: Myeloid differentiation primary response gene (88) (MYD88) is a protein that, in humans, is encoded by the MYD88 gene. By interspecific backcross mapping, the mouse MyD88 gene was localized to chromosome 9; the human homolog was mapped to 3p22-p21.3 The human ortholog MYD88 seems to function similarly to mice, however, available evidence suggests that MYD88 is dispensable for human resistance to common viral infections and to all but a few pyogenic bacterial infections, demonstrating a major difference between mouse and human immune responses.
  • Human Myeloid differentiation primary response protein MyD88 Protein information
  • Uniprot ID MYD88_HUMAN
  • Uniprot AC P78397; Q53XS7;
  • UniGene Hs.82116;
  • GeneID 4615
  • KEGG hsa:4615;
  • Human Myeloid differentiation primary response protein MyD88 Protein SEQUENCE
  • SEQUENCE 296 AA; 33233 MW; CEAE3F6B99524333 CRC64;

    MAAGGPGAGS AAPVSSTSSL PLAALNMRVR RRLSLFLNVR TQVAADWTAL

    AEEMDFEYLE IRQLETQADP TGRLLDAWQG RPGASVGRLL ELLTKLGRDD

    VLLELGPSIE EDCQKYILKQ QQEEAEKPLQ VAAVDSSVPR TAELAGITTL

    DDPLGHMPER FDAFICYCPS DIQFVQEMIR QLEQTNYRLK LCVSDRDVLP

    GTCVWSIASE LIEKRCRRMV VVVSDDYLQS KECDFQTKFA LSLSPGAHQK

    RLIPIKYKAM KKEFPSILRF ITVCDYTNPC TKSWFWTRLA KALSLP

  • UCSC uc011ayj.3; human. [Q99836-1];



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