Human IL37 ELISA Kit

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  • Alternative name

    Human FIL1 zeta ELISA Kit;Human IL-1X ELISA Kit;Human Interleukin-1 family member 7 ELISA Kit;Human IL-1F7 ELISA Kit;Human interleukin-1 homolog 4 ELISA Kit;Human IL-1H ELISA Kit;Human IL-1H4 ELISA Kit;Human Interleukin-1 zeta ELISA Kit;Human IL-1 zeta ELISA Kit;Human interleukin-1-related protein ELISA Kit;Human IL-1RP1 ELISA Kit;Human interleukin-23 ELISA Kit;Human IL-37 ELISA Kit;Human FIL1Z ELISA Kit;Human IL1F7 ELISA Kit;Human IL1H4 ELISA Kit;Human IL1RP1 ELISA Kit;Human FIL1 ELISA Kit;Human FIL1(ZETA) ELISA Kit;Human interleukin 37 ELISA Kit;Human interleukin-37 ELISA Kit;Human IL-1F7b (IL-1H4, IL-1H, IL-1RP1) ELISA Kit;Human IL-1X protein ELISA Kit;Human IL1F7 (canonical product IL-1F7b) ELISA Kit;Human interleukin 1 family member 7 ELISA Kit;Human interleukin 1, zeta ELISA Kit;Human interleukin-1 superfamily z ELISA Kit;

  • Catalog
    E019479
  • species
    Human
  • GeneIL37
  • SpecificityThe Human IL-37 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-37 proteins within the range of 15.6 pg/ml - 1000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseHuman IL37 ELISA Kit allows for the in vitro quantitative determination of IL37 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay||The Human IL-37 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-37 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human IL-37 coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-37 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human IL-37 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-37 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Interleukin 37 (IL-37) also named IL1F7, is a protein that in humans is encoded by the IL1F7 gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. And it is mapped to 2q13. In vitro expression analysis showed that IL-37 was a secretory protein. And IL-37 could play an important role in the link between innate and adaptive immunity and may be useful for tumor immunotherapy. Meanwhile, IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus. In addition, IL-37 can emerged as a dual-function cytokine with intra- and extracellular properties for suppressing innate inflammation. Furthermore, IL-37 is a new anti-inflammatory cytokine that plays an important role in protecting against tissue injury during infections via limiting immune and inflammatory reactions.
  • Human Interleukin-37 Protein information
  • Uniprot ID IL37_HUMAN
  • Uniprot AC Q9NZH6; B5BU97; Q56AP9; Q8TD04; Q8TD05; Q9HBF2; Q9HBF3; Q9UHA6;
  • UniGene Hs.166371;
  • GeneID 27178
  • KEGG hsa:27178;
  • Human Interleukin-37 Protein SEQUENCE
  • SEQUENCE 218 AA; 24126 MW; 96E089310D2CEA68 CRC64;

    MSFVGENSGV KMGSEDWEKD EPQCCLEDPA GSPLEPGPSL PTMNFVHTSP

    KVKNLNPKKF SIHDQDHKVL VLDSGNLIAV PDKNYIRPEI FFALASSLSS

    ASAEKGSPIL LGVSKGEFCL YCDKDKGQSH PSLQLKKEKL MKLAAQKESA

    RRPFIFYRAQ VGSWNMLESA AHPGWFICTS CNCNEPVGVT DKFENRKHIE

    FSFQPVCKAE MSPSEVSD

  • UCSC uc002tij.4; human. [Q9NZH6-1];


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