Human IL23A ELISA Kit

Alternative name
Human IL-23 subunit alpha ELISA Kit;Human IL-23-A ELISA Kit;Human interleukin-23 subunit p19 ELISA Kit;Human IL-23p19 ELISA Kit;Human SGRF ELISA Kit;Human IL-23 ELISA Kit;Human IL-23A ELISA Kit;Human IL23P19 ELISA Kit;Human P19 ELISA Kit;Human interleukin 23 subunit alpha ELISA Kit;Human interleukin-23 subunit alpha ELISA Kit;Human JKA3 induced upon T-cell activation ELISA Kit;Human interleukin 23 p19 subunit ELISA Kit;Human interleukin 23, alpha subunit p19 ELISA Kit;Human interleukin-six, G-CSF related factor ELISA Kit;
Catalog
E019439
species
Human
GeneIL23A
SpecificityThe Human IL-23 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-23 proteins within the range of 31.2 pg/ml - 2000 pg/ml.
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity15 pg/ml.
Intended UseHuman IL23A ELISA Kit allows for the in vitro quantitative determination of IL23A , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the Assay||The Human IL-23 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-23 in Cell Culture Supernatants, Serum, Plasma, Tissue Homogenates. This assay employs an antibody specific for Human IL-23 coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-23 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human IL-23 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-23 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Interleukin-23 subunit alpha (IL-23) is a protein that in humans is encoded by the IL23A gene. IL-23 is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration. Recently, IL-23 has been implicated in the development of cancerous tumors. he International Radiation Hybrid Mapping Consortium mapped the p19 gene to chromosome 12 (stSG47812).
Human Interleukin-23 subunit alpha Protein information
Uniprot ID IL23A_HUMAN
Uniprot AC Q9NPF7; Q6NZ80; Q6NZ82; Q9H2A5;
UniGene Hs.382212; Hs.98309;
GeneID 51561
KEGG hsa:51561;
Human Interleukin-23 subunit alpha Protein SEQUENCE
SEQUENCE 189 AA; 20730 MW; 51B5C0F188EC1B9F CRC64;
MLGSRAVMLL LLLPWTAQGR AVPGGSSPAW TQCQQLSQKL CTLAWSAHPL
VGHMDLREEG DEETTNDVPH IQCGDGCDPQ GLRDNSQFCL QRIHQGLIFY
EKLLGSDIFT GEPSLLPDSP VGQLHASLLG LSQLLQPEGH HWETQQIPSL
SPSQPWQRLL LRFKILRSLQ AFVAVAARVF AHGAATLSP
UCSC uc001sla.4; human.;

Human IL23A ELISA Kit

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