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Human IL18R1 ELISA Kit

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  • Alternative name

    Human IL-18R-1 ELISA Kit;Human IL-18R1 ELISA Kit;Human CD218 antigen-like family member A ELISA Kit;Human CDw218a ELISA Kit;Human IL1 receptor-related protein ELISA Kit;Human IL-1Rrp ELISA Kit;Human IL1R-rp ELISA Kit;Human IL1RRP ELISA Kit;Human CD218a ELISA Kit;Human IL18RA ELISA Kit;Human interleukin 18 receptor 1 ELISA Kit;Human interleukin-18 receptor 1 ELISA Kit;Human IL18Ralpha2 ELISA Kit;Human cytokine receptor ELISA Kit;
  • Catalog
    E019397
  • species
    Human
  • GeneIL18R1
  • SpecificityNatural and recombinant human IL-18R1
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman IL18R1 ELISA Kit allows for the in vitro quantitative determination of IL18R1 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the assay: human IL-18R1 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for IL-18R1 has been precoated onto 96-well plates. Standards(NSO, C22-R329) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for IL-18R1 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human IL-18R1 amount of sample captured in plate. Background: The interleukin-18 receptor 1(IL-18R1), also known as CDw218a(cluster of differentiation w218a) or IL18RA, is an interleukin receptor of the immunoglobulin superfamily. The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2(IL-1Rrp2), and IL1RL1(T1/ST2), form a gene cluster on chromosome 2q. This receptor specifically binds interleukin 18(IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells.
  • Human Interleukin-18 receptor 1 Protein information
  • Uniprot ID IL18R_HUMAN
  • Uniprot AC Q13478; B2R9Y5; Q52LC9;
  • UniGene Hs.469521;
  • GeneID 8809
  • KEGG hsa:8809;
  • Human Interleukin-18 receptor 1 Protein SEQUENCE

  • SEQUENCE 541 AA; 62304 MW; 7173DB9C7EA71D32 CRC64;

    MNCRELPLTL WVLISVSTAE SCTSRPHITV VEGEPFYLKH CSCSLAHEIE

    TTTKSWYKSS GSQEHVELNP RSSSRIALHD CVLEFWPVEL NDTGSYFFQM

    KNYTQKWKLN VIRRNKHSCF TERQVTSKIV EVKKFFQITC ENSYYQTLVN

    STSLYKNCKK LLLENNKNPT IKKNAEFEDQ GYYSCVHFLH HNGKLFNITK

    TFNITIVEDR SNIVPVLLGP KLNHVAVELG KNVRLNCSAL LNEEDVIYWM

    FGEENGSDPN IHEEKEMRIM TPEGKWHASK VLRIENIGES NLNVLYNCTV

    ASTGGTDTKS FILVRKADMA DIPGHVFTRG MIIAVLILVA VVCLVTVCVI

    YRVDLVLFYR HLTRRDETLT DGKTYDAFVS YLKECRPENG EEHTFAVEIL

    PRVLEKHFGY KLCIFERDVV PGGAVVDEIH SLIEKSRRLI IVLSKSYMSN

    EVRYELESGL HEALVERKIK IILIEFTPVT DFTFLPQSLK LLKSHRVLKW

    KADKSLSYNS RFWKNLLYLM PAKTVKPGRD EPEVLPVLSE S

  • UCSC uc002tbw.6; human.;



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