Human IL17C ELISA Kit

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  • Alternative name

    Human IL-17C ELISA Kit;Human cytokine CX2 ELISA Kit;Human CX2 ELISA Kit;Human interleukin 17C ELISA Kit;Human interleukin-17C ELISA Kit;

  • Catalog
    E019380
  • species
    Human
  • GeneIL17C
  • Other Species Mouse Il17c ELISA Kit
  • SpecificityThe Human IL-17C ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-17C proteins within the range of 125 pg/ml - 8000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseHuman IL17C ELISA Kit allows for the in vitro quantitative determination of IL17C , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay||The Human IL-17C ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-17C in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human IL-17C coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-17C present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human IL-17C antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-17C bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.
  • Human Interleukin-17C Protein information
  • Uniprot ID IL17C_HUMAN
  • Uniprot AC Q9P0M4; Q3MIG8; Q9HC75;
  • UniGene Hs.278911;
  • GeneID 27189
  • KEGG hsa:27189;
  • Human Interleukin-17C Protein SEQUENCE
  • SEQUENCE 197 AA; 21765 MW; BAE0152E18DE7D08 CRC64;

    MTLLPGLLFL TWLHTCLAHH DPSLRGHPHS HGTPHCYSAE ELPLGQAPPH

    LLARGAKWGQ ALPVALVSSL EAASHRGRHE RPSATTQCPV LRPEEVLEAD

    THQRSISPWR YRVDTDEDRY PQKLAFAECL CRGCIDARTG RETAALNSVR

    LLQSLLVLRR RPCSRDGSGL PTPGAFAFHT EFIHVPVGCT CVLPRSV

  • UCSC uc002fla.4; human.;


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