Human ICAM5 ELISA Kit

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  • Alternative name

    Human ICAM-5 ELISA Kit;Human telencephalin ELISA Kit;Human TLCN ELISA Kit;Human TLN ELISA Kit;Human intercellular adhesion molecule 5 ELISA Kit;Human intercellular adhesion molecule 5, telencephalin ELISA Kit;

  • Catalog
    E019218
  • species
    Human
  • GeneICAM5
  • SpecificityNatural and recombinant Human ICAM5
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity Intra-assay Precision Intra-Assay Precision (Precision within an assay) Three samples of kn
  • Intended UseHuman ICAM5 ELISA Kit allows for the in vitro quantitative determination of ICAM5 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay: Human ICAM5 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for ICAM5 has been precoated onto 96-well plates. Standards(Expression system for standard: NSO; Immunogen sequence: A28-E570) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for ICAM5 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Human ICAM5 amount of sample captured in plate. Background/Introduction: Intercellular adhesion molecule 5 is a protein that in humans is encoded by the ICAM5 gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
  • Human Intercellular adhesion molecule 5 Protein information
  • Uniprot ID ICAM5_HUMAN
  • Uniprot AC Q9UMF0; Q9Y6F3;
  • UniGene Hs.465862;
  • GeneID 7087
  • KEGG hsa:7087;
  • Human Intercellular adhesion molecule 5 Protein SEQUENCE
  • SEQUENCE 924 AA; 97116 MW; 97D0A9467BD16D30 CRC64;

    MPGPSPGLRR ALLGLWAALG LGLFGLSAVS QEPFWADLQP RVAFVERGGS

    LWLNCSTNCP RPERGGLETS LRRNGTQRGL RWLARQLVDI REPETQPVCF

    FRCARRTLQA RGLIRTFQRP DRVELMPLPP WQPVGENFTL SCRVPGAGPR

    ASLTLTLLRG AQELIRRSFA GEPPRARGAV LTATVLARRE DHGANFSCRA

    ELDLRPHGLG LFENSSAPRE LRTFSLSPDA PRLAAPRLLE VGSERPVSCT

    LDGLFPASEA RVYLALGDQN LSPDVTLEGD AFVATATATA SAEQEGARQL

    VCNVTLGGEN RETRENVTIY SFPAPLLTLS EPSVSEGQMV TVTCAAGAQA

    LVTLEGVPAA VPGQPAQLQL NATENDDRRS FFCDATLDVD GETLIKNRSA

    ELRVLYAPRL DDSDCPRSWT WPEGPEQTLR CEARGNPEPS VHCARSDGGA

    VLALGLLGPV TRALSGTYRC KAANDQGEAV KDVTLTVEYA PALDSVGCPE

    RITWLEGTEA SLSCVAHGVP PPDVICVRSG ELGAVIEGLL RVAREHAGTY

    RCEATNPRGS AAKNVAVTVE YGPRFEEPSC PSNWTWVEGS GRLFSCEVDG

    KPQPSVKCVG SGGATEGVLL PLAPPDPSPR APRIPRVLAP GIYVCNATNR

    HGSVAKTVVV SAESPPEMDE STCPSHQTWL EGAEASALAC AARGRPSPGV

    RCSREGIPWP EQQRVSREDA GTYHCVATNA HGTDSRTVTV GVEYRPVVAE

    LAASPPGGVR PGGNFTLTCR AEAWPPAQIS WRAPPGALNI GLSSNNSTLS

    VAGAMGSHGG EYECAATNAH GRHARRITVR VAGPWLWVAV GGAAGGAALL

    AAGAGLAFYV QSTACKKGEY NVQEAESSGE AVCLNGAGGG AGGAAGAEGG

    PEAAGGAAES PAEGEVFAIQ LTSA

  • UCSC uc002mnu.5; human.;



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