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  • Alternative name

    Human lymphokine LAG-2 ELISA Kit;Human Protein NKG5 ELISA Kit;Human T-cell activation protein 519 ELISA Kit;Human LAG2 ELISA Kit;Human NKG5 ELISA Kit;Human TLA519 ELISA Kit;Human D2S69E ELISA Kit;Human LAG-2 ELISA Kit;Human granulysin ELISA Kit;Human T-lymphocyte activation gene 519 ELISA Kit;Human lymphocyte-activation gene 2 ELISA Kit;

  • Catalog
  • species
  • GeneGNLY
  • Other Species Mouse GNLY ELISA Kit
  • SpecificityNatural and recombinant human Granulysin
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman GNLY ELISA Kit allows for the in vitro quantitative determination of GNLY , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    Principle of the assay: human Granulysin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for Granulysin has been precoated onto 96-well plates. Standards(NSO, M1-L145) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Granulysin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human Granulysin amount of sample captured in plate. Background: Granulysin is a substance released by cytotoxic T cells(CD8) when they are attached to infected body cells. The product of this gene is a member of the saposin-like protein(SAPLIP) family. It is mapped to 2p11.2. Granulysin functions to create holes in the target cell membrane and destroy it. It is able to induce apoptosis in target cells and also has antimicrobial action. This gene is expressed in cytolytic granules with perforin, a pore forming protein, and granzymes that are also involved in cytolysis. In addition to it, Granulysin is broadly antimicrobial, killing microbes that cause, for example, tuberculosis and malaria, and can destroy some tumors. A series of peptides generated from the amino acid sequence of Granulysin are potential antibiotics. It has been found that secretory Granulysin is a key molecule responsible for the disseminated keratinocyte death in SJS/TEN.
  • Human Granulysin Protein information
  • Uniprot ID GNLY_HUMAN
  • Uniprot AC P22749; P09325; Q6GU08;
  • UniGene Hs.105806;
  • GeneID 10578
  • KEGG hsa:10578;
  • Human Granulysin Protein SEQUENCE
  • SEQUENCE 145 AA; 16374 MW; CEC5432FFBDBA1F4 CRC64;




  • UCSC uc002sql.5; human. [P22749-1];

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