Human FURIN ELISA Kit

Alternative name
Human Dibasic-processing enzyme ELISA Kit;Human paired basic amino acid residue-cleaving enzyme ELISA Kit;Human PACE ELISA Kit;Human FUR ELISA Kit;Human PCSK3 ELISA Kit;Human SPC1 ELISA Kit;Human furin, paired basic amino acid cleaving enzyme ELISA Kit;Human furin ELISA Kit;Human FES upstream region ELISA Kit;Human dibasic processing enzyme ELISA Kit;Human furin, membrane associated receptor protein ELISA Kit;Human proprotein convertase subtilisin/kexin type 3 ELISA Kit;
Catalog
E015690
species
Human
GeneFURIN
Other Species Bovine FURIN ELISA Kit Mouse Furin ELISA Kit Rat Furin ELISA Kit
SpecificityNatural and recombinant human Furin
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity< 10pg/ml
Intended UseHuman FURIN ELISA Kit allows for the in vitro quantitative determination of FURIN , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the assay: human Furin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for Furin has been precoated onto 96-well plates. Standards(NSO, D108-E715) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Furin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human Furin amount of sample captured in plate. Background: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance
Human Furin Protein information
Uniprot ID FURIN_HUMAN
Uniprot AC P09958; Q14336; Q6LBS3; Q9UCZ5;
UniGene Hs.513153;
GeneID 5045
KEGG hsa:5045;
Human Furin Protein SEQUENCE
SEQUENCE 794 AA; 86678 MW; 10C44DD5892EF85D CRC64;
MELRPWLLWV VAATGTLVLL AADAQGQKVF TNTWAVRIPG GPAVANSVAR
KHGFLNLGQI FGDYYHFWHR GVTKRSLSPH RPRHSRLQRE PQVQWLEQQV
AKRRTKRDVY QEPTDPKFPQ QWYLSGVTQR DLNVKAAWAQ GYTGHGIVVS
ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG
EVAAVANNGV CGVGVAYNAR IGGVRMLDGE VTDAVEARSL GLNPNHIHIY
SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFV WASGNGGREH
DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ
IVTTDLRQKC TESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT
SKPAHLNAND WATNGVGRKV SHSYGYGLLD AGAMVALAQN WTTVAPQRKC
IIDILTEPKD IGKRLEVRKT VTACLGEPNH ITRLEHAQAR LTLSYNRRGD
LAIHLVSPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD EDPSGEWVLE
IENTSEANNY GTLTKFTLVL YGTAPEGLPV PPESSGCKTL TSSQACVVCE
EGFSLHQKSC VQHCPPGFAP QVLDTHYSTE NDVETIRASV CAPCHASCAT
CQGPALTDCL SCPSHASLDP VEQTCSRQSQ SSRESPPQQQ PPRLPPEVEA
GQRLRAGLLP SHLPEVVAGL SCAFIVLVFV TVFLVLQLRS GFSFRGVKVY
TMDRGLISYK GLPPEAWQEE CPSDSEEDEG RGERTAFIKD QSAL
UCSC uc002bpu.2; human.;

Related products with Human FURIN ELISA Kit

anti-FURIN antibody

Category

Human FURIN ELISA Kit