Human FGF23 ELISA Kit

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  • Alternative name

    Human FGF-23 ELISA Kit;Human phosphatonin ELISA Kit;Human Tumor-derived hypophosphatemia-inducing factor ELISA Kit;Human HYPF ELISA Kit;Human ADHR ELISA Kit;Human FGFN ELISA Kit;Human HPDR2 ELISA Kit;Human PHPTC ELISA Kit;Human fibroblast growth factor 23 ELISA Kit;Human tumor-derived hypophosphatemia inducing factor ELISA Kit;

  • Catalog
    E014771
  • species
    Human
  • GeneFGF23
  • Standard CurveHuman FGF23 ELISA Kit
  • Other Species Mouse Fgf23 ELISA KitRat Fgf23 ELISA Kit
  • SpecificityThe Human FGF23 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human FGF23 proteins within the range of 15.6 pg/ml - 1000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • SensitivityThe minimum detectable dose of Human FGF23 is typically less than 10 pg/ml.
  • Intended UseHuman FGF23 ELISA Kit allows for the in vitro quantitative determination of FGF23 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: FGF23, regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR). ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC). HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Belongs to the heparin-binding growth factors family. Background: Sandwich Enzyme-Linked Immunosorbent Assay for Quantitative Detection of Human FGF23 Concentrations in Cell Culture Supernatants, Serum, Plasma.
  • Human Fibroblast growth factor 23 C-terminal peptide Protein information
  • Uniprot ID FGF23_HUMAN
  • Uniprot AC Q9GZV9; Q4V758;
  • UniGene Hs.287370;
  • GeneID 8074
  • KEGG hsa:8074;
  • Human Fibroblast growth factor 23 C-terminal peptide Protein SEQUENCE
  • SEQUENCE 251 AA; 27954 MW; 6093BD0CC50C2489 CRC64;

    MLGARLRLWV CALCSVCSMS VLRAYPNASP LLGSSWGGLI HLYTATARNS

    YHLQIHKNGH VDGAPHQTIY SALMIRSEDA GFVVITGVMS RRYLCMDFRG

    NIFGSHYFDP ENCRFQHQTL ENGYDVYHSP QYHFLVSLGR AKRAFLPGMN

    PPPYSQFLSR RNEIPLIHFN TPIPRRHTRS AEDDSERDPL NVLKPRARMT

    PAPASCSQEL PSAEDNSPMA SDPLGVVRGG RVNTHAGGTG PEGCRPFAKF

    I

  • UCSC uc001qmq.1; human.;




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