Human PROCR ELISA Kit

Alternative name
Human activated protein C receptor ELISA Kit;Human APC receptor ELISA Kit;Human Endothelial cell protein C receptor ELISA Kit;Human EPCR ELISA Kit;Human CCCA ELISA Kit;Human CCD41 ELISA Kit;Human protein C receptor ELISA Kit;Human endothelial protein C receptor ELISA Kit;Human CD201 antigen ELISA Kit;Human cell cycle, centrosome-associated protein ELISA Kit;Human centrocyclin ELISA Kit;Human protein C receptor, endothelial ELISA Kit;
Catalog
E013288
species
Human
GenePROCR
SpecificityNatural and recombinant human EPCR
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity< 10pg/ml
Intended UseHuman PROCR ELISA Kit allows for the in vitro quantitative determination of PROCR , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the assay: human EPCR ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for EPCR has been precoated onto 96-well plates. Standards(NSO, S18-S210) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for EPCR is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human EPCR amount of sample captured in plate. Background: Endothelial protein C receptor (EPCR) also known as CCCA or PROCR is a protein that in humans is encoded by the PROCR gene. PRPCR gene is mapped to 20q11.2 by radiation hybrid analysis and FISH. The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
Human Endothelial protein C receptor Protein information
Uniprot ID EPCR_HUMAN
Uniprot AC Q9UNN8; B2RC04; Q14218; Q6IB56; Q96CB3; Q9ULX1;
UniGene Hs.647450;
GeneID 10544
KEGG hsa:10544;
Human Endothelial protein C receptor Protein SEQUENCE
SEQUENCE 238 AA; 26671 MW; EA7F0658CD19695C CRC64;
MLTTLLPILL LSGWAFCSQD ASDGLQRLHM LQISYFRDPY HVWYQGNASL
GGHLTHVLEG PDTNTTIIQL QPLQEPESWA RTQSGLQSYL LQFHGLVRLV
HQERTLAFPL TIRCFLGCEL PPEGSRAHVF FEVAVNGSSF VSFRPERALW
QADTQVTSGV VTFTLQQLNA YNRTRYELRE FLEDTCVQYV QKHISAENTK
GSQTSRSYTS LVLGVLVGSF IIAGVAVGIF LCTGGRRC
UCSC uc002xbt.5; human.;

Human PROCR ELISA Kit

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