Human CYR61 ELISA Kit

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  • Alternative name

    Human CCN family member 1 ELISA Kit;Human Cysteine-rich angiogenic inducer 61 ELISA Kit;Human insulin-like growth factor-binding protein 10 ELISA Kit;Human IBP-10 ELISA Kit;Human IGF-binding protein 10 ELISA Kit;Human IGFBP-10 ELISA Kit;Human Protein GIG1 ELISA Kit;Human CCN1 ELISA Kit;Human GIG1 ELISA Kit;Human IGFBP10 ELISA Kit;Human cysteine rich angiogenic inducer 61 ELISA Kit;Human protein CYR61 ELISA Kit;Human cysteine-rich heparin-binding protein 61 ELISA Kit;Human cysteine-rich, anigogenic inducer, 61 ELISA Kit;

  • Catalog
    E010723
  • species
    Human
  • GeneCYR61
  • Other Species Human Cyr61/CCN1 ELISA KitMouse Cyr61 ELISA KitChicken CYR61 ELISA KitRat Cyr61 ELISA Kit
  • SpecificityNatural and recombinant human CYR61
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman CYR61 ELISA Kit allows for the in vitro quantitative determination of CYR61 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: human CYR61 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for CYR61 has been precoated onto 96-well plates. Standards(CHO, A22-D381) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for CYR61 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human CYR61 amount of sample captured in plate. Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. This gene is mapped to 1p22.3. CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.
  • Human Protein CYR61 Protein information
  • Uniprot ID CYR61_HUMAN
  • Uniprot AC O00622; O14934; O43775; Q9BZL7;
  • UniGene Hs.8867;
  • GeneID 3491
  • KEGG hsa:3491;
  • Human Protein CYR61 Protein SEQUENCE
  • SEQUENCE 381 AA; 42027 MW; FC0BD39C078CA0B1 CRC64;

    MSSRIARALA LVVTLLHLTR LALSTCPAAC HCPLEAPKCA PGVGLVRDGC

    GCCKVCAKQL NEDCSKTQPC DHTKGLECNF GASSTALKGI CRAQSEGRPC

    EYNSRIYQNG ESFQPNCKHQ CTCIDGAVGC IPLCPQELSL PNLGCPNPRL

    VKVTGQCCEE WVCDEDSIKD PMEDQDGLLG KELGFDASEV ELTRNNELIA

    VGKGSSLKRL PVFGMEPRIL YNPLQGQKCI VQTTSWSQCS KTCGTGISTR

    VTNDNPECRL VKETRICEVR PCGQPVYSSL KKGKKCSKTK KSPEPVRFTY

    AGCLSVKKYR PKYCGSCVDG RCCTPQLTRT VKMRFRCEDG ETFSKNVMMI

    QSCKCNYNCP HANEAAFPFY RLFNDIHKFR D



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